ASTAXANTHIN REDUCES STEMNESS MARKERS IN BT20 AND T47D BREAST CANCER STEM CELLS BY INHIBITING EXPRESSION OF PONTIN AND MUTANT P53

Astaxanthin Reduces Stemness Markers in BT20 and T47D Breast Cancer Stem Cells by Inhibiting Expression of Pontin and Mutant p53

Astaxanthin (AST) is a product made from marine organisms that has been used as an anti-cancer supplement.It reduces pontin expression and induces apoptosis in SKBR3, a breast cancer cell line.Using Western blotting and qRT-PCR analyses, this study revealed that in the T47D and BT20 breast cancer cell lines, AST inhibits expression of pontin and mu

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Non-coding RNAs in Mesenchymal Stem Cell-Derived Extracellular Vesicles: Deciphering Regulatory Roles in Stem Cell Potency, Inflammatory Resolve, and Tissue Regeneration

Extracellular vesicles (EVs) are heterogeneous populations of nano- and micro-sized vesicles secreted by various cell types.There is mounting evidence that EVs have widespread roles in transporting proteins, lipids, and nucleic acids between cells and serve as mediators of intercellular communication.EVs secreted from stem cells could function as p

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Neural Correlates of Opposing Effects of Emotional Distraction on Working Memory and Episodic Memory: An Event Related fMRI Investigation

A fundamental question in the emotional memory literature is why emotion enhances memory in some conditions but disrupts memory in other conditions.For example, separate studies have shown that emotional stimuli tend to be better remembered in long-term episodic memory (EM), whereas hp victus 15-fa0031dx emotional distracters tend to impair working

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